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Cardiovascular system --- Antioxidants --- Vitamin C --- Vitamin E --- Ubiquinones --- Cardiovascular Diseases --- Review Literature. --- Treatment Outcome. --- Diseases --- Diet therapy. --- Chemoprevention. --- Therapeutic use. --- therapeutic use. --- prevention & control. --- therapy. --- Review Literature as Topic

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Quinones are members of a class of aromatic compounds with two oxygen atoms bonded to the ring as carbonyl groups. This volume covers more clinical aspects of quinines, such as anticancer properties, as well as their role in nutrition and in age-related diseases.*Mitochondrial Ubiquinone and Reductases*Anticancer Quinones and Quinone Oxido-Reductases*Quininone Reductases: Chemoprevention, Nutrition*Quinones and Age-Related Diseases

Enzymes -- Analysis. --- Enzymes. --- Glutathione. --- Quinone. --- Quinoproteins. --- Ubiquinones. --- Human Anatomy & Physiology --- Health & Biological Sciences --- Animal Biochemistry --- Amine Oxidoreductases. --- Antineoplastic agents. --- Gene Expression Regulation. --- Paracrine Communication. --- Quinone Reductases. --- Quinones. --- Ubiquinone. --- Xenobiotics. --- Ubiquinone --- Quinones --- Enzymes --- Organic Chemicals --- Enzymes and Coenzymes --- Coenzymes --- Benzoquinones --- Chemicals and Drugs --- Cofactors, Enzyme --- Enzyme Cofactors --- Coenzymes and Enzymes --- Chemicals, Organic --- Biocatalysts --- Coenzyme Q --- 2,5-Cyclohexadiene-1,4-Diones --- o-Benzoquinones --- p-Benzoquinones --- 1,2-Benzoquinones --- 1,4-Benzoquinones --- Benzodiones --- Cyclohexenes --- Molecular Mechanisms of Pharmacological Action --- Coenzyme --- Enzyme Cofactor --- Cofactor, Enzyme --- Organic Chemical --- Chemical, Organic --- Biocatalyst --- Enzyme

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This book offers a comprehensive exploration of research on the essential relationship of the coenzyme Q10 and the process of aging in living organisms. CoQ10 is an important factor in two main aspects of cell physiology: bioenergetics and antioxidant protection. While primary deficiency of CoQ10 is associated with severe and lethal disease, secondary deficiency can be associated with the progression of mitochondrial dysfunction linked to the lessening of biological activities during aging. The book is organized in four sections. The first offers an overview of the function of CoQ10, highlighting the two main functions of CoQ10 in cells: its essential role as electron transport chain member in mitochondria, and the protection of cell membranes against oxidation as one of the main endogenous-synthesized antioxidants. The second section covers research on Coenzyme 10. Topics include studies involving invertebrate models, mammal studies and the influence of CoQ on longevity. Also covered is research involving the role of CoQ in senescence-accelerated mice. Section three examines the effects of reduced CoQ in human aging, as evident in mitochondrial dysfunction, metabolic syndrome, neurodegenerative disorders, immunosenescence and fertility and reproduction. The final section, Prolongevity effectors and Coenzyme Q, explores research into slowing or stopping the aging process. Coverage includes strategies including calorie restriction, and modulation of CoQ10 levels by induction of synthesis or by supplementation. Coenzyme Q in Aging benefits a broad readership of researchers, clinicians, educators and students interested in the biochemical and physiological effects of coenzyme Q and the importance of this molecule in aging process.

Medicine. --- Cell biology. --- Internal medicine. --- Biochemistry. --- Physiology. --- Biomedicine, general. --- Cell Biology. --- Internal Medicine. --- Biochemistry, general. --- Animal physiology --- Animals --- Biology --- Anatomy --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Chemistry --- Medical sciences --- Medicine, Internal --- Medicine --- Cell biology --- Cellular biology --- Cells --- Cytologists --- Health Workforce --- Physiology --- Composition --- Ubiquinones --- Physiological effect. --- Coenzyme Q --- Coenzyme Q10 --- Dimethoxymethylbenzoquinone --- Coenzymes --- Isopentenoids --- Quinone --- Envelliment --- Coenzims --- Citologia --- Biologia cel·lular --- Biologia --- Citogenètica --- Citoquímica --- Migració cel·lular --- Cèl·lules --- Cèl·lules animals --- Ultraestructura (Biologia) --- Enzims --- NAD (Coenzim) --- Senectut --- Biologia del desenvolupament --- Persones de mitjana edat --- Persones grans --- Gerontologia --- Longevitat --- Envelliment cerebral --- Factors d'edat en les malalties